"The one who figures out everything by himself, certainly goes wrong."
Japanise proverb
Dr Lajos Haracska
Education:
B.Sc., Molecular Biology and Biotechnology, 1991 József Attila University, Szeged, Hungary
Ph.D., Biochemistry, 1998 József Attila University, Szeged, Hungary
Employment history:
2004-present, group leader, staff scientist, Institute of Genetics, Biological Research Center, Szeged, Hungary
1998-2004, research fellow, University of Texas Medical Branch, Galveston, USA
1997-1998, postdoctoral fellow, The Medical
Sciences Institute, Dundee, UK
1995-1998, PhD student, Biological Research Center, Szeged, Hungary
1991-1995, research fellow, Institute of Biochemistry, Szeged, Hungary
Awards, fellowships:
1996 Excellent young Researcher Award of The Hungarian Academy of Sciences
1997 EMBO short term fellowship
1997 FEBS short term fellowship
2003 Wellcome Trust International Senior Research Fellowship in Biomedical Science
2005 Howard Hughes Medical Institute Award
2006 Marie Curie Fellowship
Dr Péter Burkovics
Date of birth:
November 01, 1978
Place of birth:
Szeged, Hungary
Marital status:
Single
Education and training:
University of Szeged, Hungary, Biology (cellular and molecular biological specialization)
1997 - 2002 (Degree equivalent to M.Sc)
Ph.D. student of molecular biology (2002 – 2006)
University of Szeged, Hungary, and Biological Research Center of the Hungarian Academy of Sciences,
Role of the human Ape2 protein in the DNA repair,
PhD thesis (summa cum laude 2006)
Research adviser: Lajos Haracska PhD
Staff scientist, Laboratory of Dr. Lajos Haracska, Institute of Genetics, BRC HAS, 2007 -
Academic appointment:
2005 - 2008 Young Scientist Research Fellow, Hungarian Academy of Sciences, Biological Research Center, Szeged, Hungary
Fellowships:
2002. Hungarian Republic Fellowship
Teaching field:
2003 – 2004: Comparative Anatomy (practical course), and Cell Biology (practical course), University of Szeged
Research interest:
Role of Ape2 protein in the DNA repair
Posttranslational modification of the DNA repair proteins
Regulation of the DNA repair pathways
Publications:
Peter Burkovics , Valeria Szukacsov , Ildiko Unk , and Lajos Haracska
Human Ape2 protein has a 3'-5' exonuclease activity that acts preferentially on mismatched base pairs.
Nucleic Acids Res. 2006 May 10;34(9):2508-15. Print
2006.
Kortvely E, Burkovics P, Varszegi S, Gulya K.
Cloning and characterization of rat importin 9: implication for its neuronal function.
Brain Res Mol Brain Res. 2005 Sep 13;139(1):103-14.
András Blastyák
Former Member
Date and country of birth:
28. 12. 1972, Hungary
Education:
University of Szeged, 1991-1996
Degree equivalent to M.Sc
University of Szeged Faculty of Science
Doctoral Program in Biology 2006-
Employment:
Laboratory of Henrik Gyurkovics and János Gausz
Institute of Genetics, BRC HAS
Laboratory of Francois Karch
University of Geneva, Switzerland
(supported by an EMBO Short Term Fellowship)
Laboratory of Lajos Haracska
Institute of Genetics, BRC HAS
Research experience:
Drosophila genetics and molecular biology
Yeast genetics and molecular biology
DNA-protein interactions
Valéria Szukacsov
Date and country of birth: 16. 07. 1975, Hungary
Education:
University of Szeged, 1998-2003
Degree equivalent to M.Sc
University of Szeged Faculty of Science 2003-
Ph.D. student of molecular biology
Research experience:
Undergraduate student 1998-2003
Laboratory of Dr. Éva Monostori
Institute of Genetics, BRC HAS
Ph.D student 2003-
Laboratory of Dr. Lajos Haracska
Institute of Genetics, BRC HAS
Research interest:
Posttranslational modification of the DNA repair proteins
Regulation of the DNA repair pathways
Publications:
1. Legradi A, Chitu V, Szukacsov V, Fajka-Boja R, Szekely Szucs K, Monostori E.
Lysophosphatidylcholine is a regulator of tyrosine kinase activity and intracellular Ca(2+) level in Jurkat T cell line.
Immunol Lett. 2004 Jan 30;91(1):17-21.
2. Burkovics P, Szukacsov V, Unk I, Haracska L.
Human Ape2 protein has a 3’-5’exonuclease activity that acts preferentially on mismatched base pairs
Nucleic Acids Res. 2006 Apr 13
Lajos Pintér
Date and country of birth:
04.27.1979, Hungary
Education:
University of Szeged, 1998-2003
Degree equivalent to M.Sc in Genetics and Molecular Biology
University of Szeged Faculty of Science 2003-
Ph.D. student
Research experience:
Undergraduate student 2000-2003
Laboratory of Dr. Henrik Gyurkovics
Institute of Genetics, BRC HAS
Maintenance of active and inactive chromatine structure in Drosophila Melanogaster
Ph.D student 2003-
Laboratory of Dr. Lajos Haracska
Institute of Genetics, BRC HAS
Structural and functional analysis of hRev3
Awards and Fellowships:
2003 National Competition of Undergraduate Students 1. place in section of molecular biology
2006-2009 Young Scientist Research Fellow, Hungarian Academy of Sciences, Biological Research Center, Szeged, Hungary
Publications:
2007: Blastyák András; Pintér Lajos; Unk Ildiko; Prakash Louise; Prakash Satya; Haracska Lajos
Yeast Rad5 protein required for postreplication repair has a DNA helicase activity specific for replication fork regression.
Molecular cell 2007;28(1):167-75.
Yatish J. Achar
Education:
BSc (2000) University Of Mysore, Hassan, India
MSc Biotechnology (2002) University of Mysore, Mysore, India
Career history:
2002-2004: Research scientist, Institute of Bioinformatics, Bangalore India
2004-2004: Senior Research fellow, Avesthagen ltd, Bangalore India
2004-2005: Research trainee, International training course, BRC, Szeged, Hungary
2005-onwards: PhD student, Hungarian academy of sciences, Szeged, Hungary
Gali Himabindu
SYNOPSIS:
Currently as a PhD student at Institute of Genetics, Biological Research Centre,Szeged (September 2006)
ITC Fellow (International Training Course) at Biological
Research Centre, Szeged (October 2005 – August 2006)
Research assistant in Cell and Tissue Engineering project at CCMB, Hyderabad ( November 2003 – May2005)
Research assistant in comparative genomics work at Centre for Human Genetics, Bangalore (May 2003 - November 2003).
Completed MSc. in Biotechnology, from University Of Mysore (July-2002)
EDUCATIONAL QUALIFICATIONS:
1995 - School of secondary examination from board of secondary education. First division with distinction
1997 - Higher secondary examination from board of Intermediate education. First division.
2000 - B.Sc. in Microbiology, Genetics & Chemistry from Osmania University, Hyderabad, First Division.
2002 - M.Sc. in Biotechnology from University of Mysore, Mysore. Distinction
PERSONAL INFORMATION:
Date of Birth : 20th April 1979
Father’s name : G. Jayaram Chowdary
Nationality : Indian
Marital status and sex : Unmarried, Female
Languages known : English, Hindi, Telugu & Kannada
Zoltán Gyuris
Former Member
Education:
Molecular biology 2002-2007 University of Szeged
PhD student (Multidisciplinar Medical School) 2007-
Employment history:
2003-2007 Genetic laboratory in Second Department of Internal Medicine and Cardiological Center, Szeged
2007- Mutagenesis and Carcinogenesis Research Group,
Biological Research Center, Hungarian Academy of Sciences, Szeged
Citation list:
1) Gyuris Z, Sepp R, Endreffy E, Hortobágyi T, Pap R, Sághy L, Pálinkás A, Csanády M, Forster T. A dystrophin gén mutációjának igazolása izomdystrophia asszociált dilatatív cardiomyopathiában Magyar Humángenetikusok V. Munkakonferenciája. Szeged, 2004. november 11-13.
2) Gyuris Z, Sepp R, Csanády M, Napolitano C, Sághy L, Jebelovszki É, Priori S, Schwartz PJ, Anastasakis A, Forster T. Az első KCNE1 génmutáció azonosítása magyar hosszú QT szindrómás betegben. A Magyar Kardiológusok Társaságának 2005. évi Tudományos Ülése. Balatonfüred, 2005. május 11-14.
3) Botos A, Sepp R, Losonczi L, Gyuris Z, Görög M, Csanády M, Forster T. A repolarizáció kvalitatív paramétereinek elemzése genotipizált hosszú QT-szindrómás betegekben. A Magyar Kardiológusok Társaságának 2006. évi Tudományos Ülése. Balatonfüred, 2006. május 10-13.
4) Csanády M, Sepp R, Botos A, Losonczi L, Görög M, Gyuris Z, Forster T: Clinical and molecular genetic screening in familial long QT syndrome. 14th Alpe Adria Cardiology Meeting, 3-7 May, 2006, Cavtat-Dubrovnik, Croatia.
5) Görög M, Sepp R, Losonczi L, Gyuris Z, Botos A, Csanády M, Forster T. Klinikai és molekuláris genetikai családszűrés familiáris hosszú QT szindrómában. A Magyar Kardiológusok Társaságának 2006. évi Tudományos Ülése. Balatonfüred, 2006. május 10-13.
6) Csanády M, Sepp R, Gyuris Z, Görög M, Forster T. Genetikai vizsgálatok jelentősége hypertrophias cardiomyopathiában. A Szegedi Akadémiai Bizottság Orvostudományi Szakbizottságának Kardiológiai Munkacsoportja Tudományos Ülése. Szeged, 2006. szeptember 19.
Quotable abstracts:
1) Gyuris Z, Sepp R, Csanády M, Napolitano C, Sághy L, Jebelovszki É, Priori S, Schwartz PJ, Anastasakis A, Forster T. Az első KCNE1 génmutáció azonosítása magyar hosszú QT szindrómás betegben. Cardiologia Hungarica 2005; 35: A31.
2) Görög M, Sepp R, Losonczi L, Gyuris Z, Botos A, Csanády M, Forster T. Klinikai és molekuláris genetikai családszűrés familiáris hosszú QT szindrómában. Cardiologia Hungarica 2006; 36: A37.
3) Csanády M, Sepp R, Botos A, Losonczi L, Görög M, Gyuris Z, Forster T. Clinical and molecular genetic seerning in familial long QT syndrome. 14th Alpe Adria Cardiology Meeting. Abstact Book of Alpe Adria Meeting (Liječnički Vjesnik) 2006; 56. old.
4) Botos A, Sepp R, Losonczi L, Gyuris Z, Görög M, Csanády M, Forster T. A repolarizáció kvalitatív paramétereinek elemzése genotipizált hosszú QT-szindrómás betegekben. Cardiologia Hungarica 2006; 36: A15.
Katalin Kovács
Technician
Ildikó Kravjár
Technician
Ica Notári
Technician
Barnabás Szakál
Former Member
Szilvia Juhász
Dávid Balogh
Adrienn Hajdu
Zoltán Varga-Orvos
Former Member
Educations:
1997-2004. Szent-Györgyi Albert Medical University (present: University of Szeged), Szeged
2004-2007. PhD student in Postgradual Program of Biology, University of Szeged (laboratory work for Laboratory of Functional Genomics (P.I: László Puskás), Biological Research Center, Hungarian Academy of Sciences)
2007- Scientific member of Mutagenesis and Carcinogenesis Research Group (P.I.: Lajos Haracska), Biological Research Center, Hungarian Academy of Sciences, Szeged, Hungary
Qualifications:
2004. Doctor of Medicine (summa cum laude): Szent-Györgyi Albert Medical University (now: University of Szeged), Szeged, Hungary
Workplaces, research experience:
2004-2007. Laboratory of Functional Genomics, Biological Research Center, Hungarian Academy of Sciences
Awards, honours:
University competiton of genetics for undergraduate students, 1. place, 1998
National Competiton named after Krompecher Ödön (title of essay: Neuroendocrin system and it’s tumours), 1. place, 2001
Local Scientific Conference for undergraduate students (title of lecture: Prognostic factors and survival of patients with malignant
melanoma giving metastases into the brain), 3. place, 2003
National Competition for undergraduate students Epidemiology Section (title of lecture: Prognostic factors and survival of patients
with malignant melanoma giving metastases into the brain), 4. place, 2003
Competition 2004 announced by Novartis (title of essay: What can a pathologist do to make a right diagnosis of neuroendocrin
tumours of alimentary tract, 1. place, 2004
Károly Fátyol
Former Member
Ildikó Hajdú
Former Member
Date and country of birth: 06.06.1978, Hungary
Education: University of Szeged, 1998-2003
Degree equivalent to M.Sc
University of Szeged Faculty of Science 2003-
Ph.D. student of molecular biology
Research experience: Undergraduate student 2000-2003
Laboratory of Dr. Istvan Kiss
Institute of Genetics, BRC HAS
Novel screen for dp53 interacting
genes in Drosophila melanogaster
Ph.D student 2003-
Laboratory of Dr. Lajos Haracska
Institute of Genetics, BRC HAS
Study of HLTF and SHPRH as the
human homologues of yRad5
Overseas experience: The University of Texas Medical
Branch
Sealy Center for Molecular Science
Laboratory of Dr. Louise Prakash
February-May, 2006
In vitro protein-protein interaction
studies
The University of Manchester
Laboratory of Dean Alan Jackson
June-September, 2006
Progression of replication in Rad18-/-
cell lines
Publications:
Unk I*, Hajdu I*, Fatyol K, Bermudez V, Hurwitz J, Yoon Jung Hoon, Prakash L, Prakash S, Haracska L.
Human HLTF functions as a ubiquitin ligase for PCNA poliubiquitination.
PNAS, 2008 Mar 11;105(10):3768-73.
* Contributed equally
Unk I, Hajdu I, Fatyol K, Szakal B, Blastyak A, Bermudez V, Hurwitz J, Prakash L, Prakash S, Haracska L.
Human SHPRH is a ubiquitin ligase for Mms2-Ubc13-dependent polyubiquitylation of proliferating cell nuclear antigen.
PNAS, 2006 Nov 28;103(48):18107-12
Róbert Tóth
Undergraduate Student
Dr Móni Mórocz
Dr Katalin Priskin
Szilvia Bakó
Undergraduate Student
Beáta Szilvia Bolla
Undergraduate Student
Katinka Barasevich
Undergraduate Student
Márton Zsolt Enyedi
