"What limit can be put to this power, acting during long ages and rigidly scrutinising the whole constitution, structure, and habits of each creature, - favouring the good and rejecting the bad? I can see no limit to this power, in slowly and beautifully adapting each form to the most complex relations of life. "
Charles Darwin
Genomic DNA is subjected to damage by both external environmental agents and endogenous metabolic processes. To maintain the integrity of the genome, a variety of repair mechanisms have evolved that remove damaged bases from DNA. However, sometimes DNA damage is not repaired before replication takes place due to mutations in repair systems, limited cellular repair capacity, or timing...more
Welcome, to the site of the "Mutagenesis and Carcinogenesis Research Group".
The lab was estabilshed in 2003 under the leadership of Lajos Haracska in the Genetics Institute of the Biological Research Center at Szeged Hungary.
Our mission is to have a deeper understanding about the repair of the thousands of damages that form on our DNA every day.