| Synthetic and Systems Biology Unit Biological Research Centre |
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Synthetic and Systems Biology Unit Biological Research Centre of the Hungarian Academy of Sciences H-6726 Szeged Temesvári krt. 62. Hungary |
Systems and synthetic biology are complementary disciplines
which aim at understanding the design principles and multi-level
properties of large cellular subsystems arising from numerous molecular
interactions. While recent technological advancements has enabled the
rapid collection of data on the molecular components of cells and their
interactions, there is an increasing need for automated experimental and
computational methods that analyse both normal cellular physiology and
the phenotypic impact of mutations and environmental perturbations
(e.g., drug treatments). The unicellular yeast, Saccharomyces cerevisiae and Escherichia coli are
ideal candidates for systems and synthetic biology studies due to the
availability of large and diverse sets of post-genomic information and
genome engineering tools. The Unit is developing new experimental and computational approaches in the fields of genome engineering and systems biology to address fundamental problems in biology and medicine. Kiss Lab (DNA-Protein Interactions)
Pál Lab (Experimental Evolution) Papp Lab (Computational Systems Biology) Pósfai Lab (Genome Engineering) |
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